Clinical Studies II

Study 2

Objective: To study the effect of gum guggul on the serum fibrinolytic activity (FA) and platelet adhesive index (PAI).

Methods: Healthy subjects (20) and patients of coronary heart disease were divided into control and treated subgroups. The treated groups received a gum guggul fraction of 0.5 g twice daily in a gelatin capsule for 30 days. Withdrawn blood samples were analyzed for fibrinolytic activity and platelet adhesive index.

Results:

Figure 22
Effect of gum guggul on the fibrinolytic activity of healthy subjects.

Figure 23
Effect of gum guggul on the fibrinolytic activity of CAD patients.

 

Figure 24
Effect of gum guggul on the platelet adhesive index in healthy subjects.

Figure 25
Effect of gum guggul on the platelet adhesive index in CAD patients.

Conclusions::The gum guggul fraction reduced platelet adhesiveness and increased the blood’s fibrinolytic activity (i.e. fibrin-breaking activity), two actions that are extremely beneficial in protecting against heart attack and stroke (thrombosis). The activity persisted as long as the gum guggul was taken.